Conversely the proportion of neutrophils (3.5% in CTCs vs. 0.00002% in HD), monocytes (20.9% in CTC vs. 3.6% in HD), and CD8 T cells (28.7% in CTCs vs. 10.4% in HD) increased in CTC cultures vs HD samples (Figure 4b). Here, CD8A is linked to Huntington disease.