It has been found that asialoglycoprotein receptor (ASGPr), a C‐type lectin primarily expressed on the surface of liver parenchymal cells and hepatic cancer cells,[26] could selectively bind to the galactose residue of lactose and facilitate the process of endocytosis.[27, 28, 29] Therefore, taking advantage of ASGPr‐mediated targeting property of lactose might strengthen therapeutic effects of liver diseases. The gene discussed is ASGR1; the disease is liver disorder.