The expressions of AD related p‐Tau (Thr181), BACE1, pGSK3β (Tyr216), β‐amyloid precursor protein (APP) and presenilin 1 (PS1) were significantly decreased in the MSC‐treated group in hippocampus (Figure 2A,E) and/or cerebral cortex (Figure S2, Supporting Information) compared with that in the PBS group. This evidence concerns the gene APP and Alzheimer disease.