Increased endothelial and tumor cell expression of adhesion proteins including intracellular adhesion molecules (e.g. I‐CAM, E‐selectin), CD44, integrin α4, integrin α5, and integrin β1 has been reported after radiotherapy treatment with doses between 2 and 20 Gy.81, 82, 83, 84, 85. This evidence concerns the gene CD44 and neoplasm.