Yamamoto et al. independently investigated the effects of OMD on the adipogenesis of 2D cultured 3T3-L1 cells by comparing with the effects of PGF2α and reported the following findings; (1) the lipid staining by Oil Red O was significantly inhibited by LAT and PGF2α, but not by OMD, and (2) LAT and PGF2α significantly suppressed adipogenesis related gene expression, but OMDI had no effect12. This evidence concerns the gene LAT and occult macular dystrophy.