Despite TRIM29 plays both promotive and suppressive roles in different cancers, a previous study reported that TRIM29 was upregulated and correlated with poor prognosis in TC patients, and functions as a oncogene via P13K/AKT signaling pathway24, another study observed that TRIM29 regulated cell growth via LncRNA HOXA11-AS/miR-761/TRIM29 axis25. The gene discussed is TRIM29; the disease is cancer.