CPSF6 and infection: An artificial construct composed of rhesus tripartite motif-containing (TRIM) 5 ring, B-box 2, and coiled-coil elements fused to CPSF6-358 similarly restricted infection by HIV-1 and SIVmac without perturbing MLV, EIAV, FIV, or bovine immunodeficiency virus (BIV) infection (35).