From this information, it can be considered for the analysis if hsa-miR-933 can regulate the overexpressed PEA15, downregulated BDNF, or other ATF2 target genes (PRKACB, GNAS, PRKCE, and MAP4K4) to control type II diabetes mellitus (Fig. 4b). This evidence concerns the gene MAP4K4 and type 2 diabetes mellitus.