There was a statistically significant (p = 0.029) correlation of high levels of CREB expression with increased overall survival, while the survival of RCC patients did not statistically significant differ with the HLA-G expression (membranous or cytoplasmic) or HLA-E expression (p = 0.965, p = 0.56 and p = 0.216, respectively). This evidence concerns the gene HLA-G and renal cell carcinoma.