NRGN and Lewy body dementia: While some are directly related to α-syn, such as the α-syn oligomers, fibrils, or phosphorylation on S129 of α-syn, there are other post-translational modifications or even biomarkers which are unrelated to the direct aggregation processes of α-syn, such as YKL-40, neurogranin, and VILIP-1 (for review, see [8]); yet these biomarkers suffer from a lack of hindsight to determine if they are actually relevant in the biological diagnosis of DLB.