When comparing among patients with narcolepsy-cataplexy (NT1), NPC and IHS, the median of the CSF orexin levels were 42.5 pg/mL (25–75%: 40, 58.8 pg/ml), 205 pg/mL (139, 239 pg/ml), 292 pg/mL (242.3, 361.5 pg/ml) respectively (Fig. 2). This evidence concerns the gene HCRT and narcolepsy-cataplexy syndrome.