Additionally, overexpression of IGF2BP3 also indicated poor OS in various tumors, including kidney renal clear cell carcinoma (KIRC), kidney renal papillary cell carcinoma (KIRP), brain lower grade glioma (LGG), lung adenocarcinoma (LUAD), mesothelioma (MESO) and sarcoma (SARC) (Fig. 2 a, b). This evidence concerns the gene IGF2BP3 and lung adenocarcinoma.