AGT and COVID-19: From these pleiotropic actions, statins have been purposed to reduce the occurrence and severity of ARDS states and the effects of endotoxin in lung injury [137–141], acting against COVID-19, particularly in the second and third stages [104, 142–145], in addition to the effects on the RAAS, including the decrease of angiotensin II synthesis and action, and reduction of the RAAS-induced oxidative state [146–148].