The factors related to the progression of CIN that were identified in part 3.2, including older age, premenopause and multiple parity as well as significantly differentially expressed genes TGFBR2, FOXO1, CSKN1A1, PRKCI, and CTBP2, were included in the univariate logistic analysis. The gene discussed is CTBP2; the disease is cervical squamous intraepithelial neoplasia.