According to the experimental results, it is speculated that the overexpression of CSNK1A1 has no effect on CTNNB1 during the progression of CIN, so it may not promote cell proliferation or even malignancy through pathways other than the Wnt/β-catenin signaling pathway(Fig. 7). The gene discussed is CTNNB1; the disease is cervical squamous intraepithelial neoplasia.