Some miRNAs involved in the pathophysiological inflammatory process of sepsis based on endotoxin (LPS) activation of TLR4 in the signaling pathway of NF-κB activation, pro-inflammatory cytokine production (IL-6, IL-1β, TNFα) and subsequent neutrophil activation, damage of endothelial permeability and tissue injury are: miR-146 a/b, miR-223, miR-155, miR-203, miR-15a, miR-16, miR-126, miR-199a and miR-9. This evidence concerns the gene IL6 and Sepsis.