In fact, Brembilla et al. [80] found that IL-17 stimulation did not regulate the expression of Col I by dermal fibroblasts of SSc patients and Carvalheiro et al. [81] showed that IL-17 neutralization did not affect the expression of collagen family members by dermal fibroblasts, by reducing the expression of fibrotic mediators such as IL-6. This evidence concerns the gene IL17A and systemic sclerosis.