In general, the detected effects in two CRC clusters were relatively small, not exceeding absolute log fold change (logFC) = 1, with the exception of ATG4A, ATG4D, ATG9B, DRAM1, GABARAPL1, and ULK4. For these genes, absolute logFC values were above 1; however, it was not consistent across datasets and/or clusters except for DRAM1, for which logFC > 1 was noted in cluster 2 in both datasets. The gene discussed is DRAM1; the disease is colorectal carcinoma.