SFTPA1 and COVID-19: Given the sex-specific and the SP-A genotype specific outcomes in animal models [41,42,79,86,88] and the important role of innate immunity in providing the first line of defense, it is highly likely that the genetics of the innate immunity molecule, SP-A, contribute to and/or may partly explain the differential outcome in COVID-19 patients under different lung microenvironments [89,90].