PRNP and Hodgkins lymphoma: On ligand blots, purified recombinant PrPc 23–231 binds to the hnRNP A2/B1 and aldolase C from the cytosolic fraction of brain homogenate obtained from PrPc knockout mice and Co-IP with a cytosolic fraction of human Hodgkin’s lymphoma cells confirmed the interaction between these proteins [48].