ITPKC and necrotizing vasculitis: Inositol 1,4,5-trisphosphate 3-kinase C (ITPKC), encoded by the ITPKC gene on chromosome 19q13.2, is known to be associated with Kawasaki disease, a pediatric disorder characterized by hyperactive T cells affecting the medium-sized arteries producing multi-systemic vasculitis predominantly seen in a Far East Asian population [30,31,32,33].