Even though GSN mRNA levels were decreased in many hemato-oncologic diseases, MDS-EB-2 and chronic myeloid leukemia in an accelerated phase showed increased levels of GSN, suggesting that the pathological conditions with rapidly increasing clones might be different with stable conditions in MDS and chronic myeloid leukemia. Here, GSN is linked to chronic myelogenous leukemia, BCR-ABL1 positive.