BRD7 and breast cancer: Moreover, through its N-terminus, BRD7 binds to Y box binding protein-1 (YB1) [40], an oncogene that is upregulated in certain cancers [86]; this in turn leads to ubiquitin-mediated degradation of YB1 in the MDA231 and MCF7 breast cancer cell lines (Figure 3C) [40].