We have previously found the dead box polypeptide 43 (DDX43; helicase antigen (HAGE)) to be one of the most frequently expressed cancer-testis antigens in adult AML [26] and in this study we found significant differences in HAGE expression between intermediate and good risk subgroups of adults with AML (p = 7.69 × 10−3). The gene discussed is DDX43; the disease is acute myeloid leukemia.