Interestingly, FDG uptake in WT1-vaccinated skin continued for more than 858 days in patient 17 whose stage IV pancreatic cancer reached operable levels as a result of WT1 vaccine therapy and who was cured with a subsequent operation.[11] The WT1-vaccinated skin of this patient could maintain its inflammatory status for years, and such strong and sustained immunity might be associated with the good clinical course. This evidence concerns the gene WT1 and familial pancreatic carcinoma.