TNF and rheumatoid arthritis: It is reported that, for instance, Zhuang medicine cupping combined with pricking blood therapy can improve the clinical symptoms of arthralgia disease patients significantly (Zeng et al 2008).[12] Besides, Zhuang medicine thread Moxibustion can obviously reduce the levels of serum tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) (Xu et al 2014).[13] Through many clinical samples, it is fully realized that Zhuang medicine has its advantages in treating RA, even in curative effects, it is greater than Western medicine, with fewer adverse reactions.