A mutation in the TNFRSF13B gene (c.431C > T, p.Ser144Leu) was found in the current patient by exome sequencing, and a gain-of-function mutation in TNFRSF13B was reported as a candidate for the predisposition to familial or sporadic immune thrombocytopenia.[13] Therefore, the disease etiology in these patients may be related to gene mutations. This evidence concerns the gene TNFRSF13B and autoimmune thrombocytopenic purpura.