ADGRA2 and intracerebral hemorrhage: Genetic ablations of canonical Wnt signaling components in mice including the Wnt ligand Wnt7a/7b and agonist Norrin,30, 31, 32, 33 receptor/co‐receptors Fzd4, Lrp5/6, Gpr124, or Reck,31, 41 or effector Ctnnb1 (β‐catenin),30, 33, 39, 42, 43 compromises BBB formation or integrity, accompanied by widespread or focal intracerebral hemorrhage (ICH).