Diseased Mx1-Cre KrasLSL-T58I/+ and Mx1-Cre KrasLSL-P34R/+ mice had significantly elevated blood leukocyte counts, with increased numbers of lymphocytes, neutrophils, and monocytes as well as mild anemia and splenomegaly (Figure 7, B and C, and Supplemental Table 4). The gene discussed is MX1; the disease is Splenomegaly.