WWTR1 and cancer: WWTR1 gene expression showed significant negative correlation with its dependency in these 273 cancer cell lines (Pearson R = −0.570, p-value=3e-25) and showed non-significant negative correlation among our 21 OSCC lines screened (Pearson R = −0.354, p-value=0.116) (Figure 3—figure supplement 3B–C).