G3BP1 and gastric cancer: Cancer cells, exposed to the conditions of hypoxia, nutrient starvation or chemotherapy-induced high reactive oxygen species, are expected to promote eukaryotic initiator factor 2A phosphorylation-triggered SGs assembly.36 In addition, it has been established that SGs act as storage sites for non-translating mRNAs separated from disassembled polysomes;13 thus, G3BP1, an essential component of SGs, might also be involved in the regulation of apoptosis and the response to chemotherapy in gastric cancer, as investigated in this study.