In addition, another apoptosis marker, the TUNEL (terminal deoxynucleotidyl transferase dUTP nick-end labelling) score, of MGC80-3 xenograft tumours was significantly increased in the G3BP1-depleted group compared to the control group upon capecitabine treatment, while the proliferation index (Ki-67 score) was largely decreased in the shG3BP1 group relative to the control group (Supplementary Fig. 4d–f). The gene discussed is G3BP1; the disease is neoplasm.