Compared to the controls (regular chow or RC), Ephx2 mRNA level was significantly increased in the iBAT of high fat-fed obese C57BL/6J mice (HF) (p < 0.05), but was not changed in the epididymal WAT (eWAT) (p < 0.05) (Figure 1C). This evidence concerns the gene EPHX2 and hydrops fetalis.