Several studies have demonstrated the relationship between PWV values and lipid profile (total cholesterol, low-density-lipoprotein [LDL]-cholesterol, triglycerides), insulin resistance (Homeostatic Model Assessment of Insulin Resistance [HOMA-IR]), fasting insulin, and C-reactive protein (CRP) in children with obesity [11,12,13]. This evidence concerns the gene CRP and obesity due to melanocortin 4 receptor deficiency.