TGFBR3 gene downregulation has been stated in the case of different cancers, and the observed decline in the expression of the TGFBR3 gene appears to be correlated with cancer progression, when tumor cells demonstrate an increase invasiveness and metastatic potential [17,18,19,20,21,22,23,25,26,27,28]. This evidence concerns the gene TGFBR3 and neoplasm.