LRRK2 and tuberculosis: In the GSE20050, we found that when compared with normal lung parenchyma, LRRK2 was significantly down-regulated in caseous tuberculosis granulomas (p = 0.0361), but CCR7 and FYN was upregulated (p = 0.0024 and p = 0.0486, respectively) (Figure S4) [27].