Among the genes of the amplicon, mRNA expression is imperfectly associated with amplification with the higher number of cases with mRNA over-expression observed for ERLIN2, PLPBP, BRF2, RAB11FIP1, ASH2L, LSM1, DDHD2 and NSD3 in cancers with the amplicon. The gene discussed is ERLIN2; the disease is cancer.