Among cohorts of patients with all sub-types of breast cancer, patients with higher expression (the higher quartile of the cohorts) of EIF4EBP1 and LSM1 mRNA had worse Relapse-Free Survival (RFS) than patients with lower expression of either genes, suggesting that the two genes act as oncogenes (Figure 8A and Figure 9A). The gene discussed is LSM1; the disease is breast cancer.