MiR-142-3p, downregulated in CD4 T cells and peripheral blood from TB patients [39] and in M. bovis-infected macrophages [60], negatively regulates the expression of inflammatory cytokines, like NF-κB, TNF-α, and IL-6, in part by targeting the IRAK1 gene [60]. The gene discussed is NFKB1; the disease is tuberculosis.