Additionally, the combined study of these two biomarkers, ECM1 and TEX101 permit the differentiation of different NOA subtypes, due to the specific expression of TEX101 in testicular germ cells, thus providing a non-invasive clinical assay with the potential to eliminate diagnostic testicular biopsies and improve the confidence of azoospermia diagnosis [10,124]. Here, TEX101 is linked to Azoospermia.