SAMHD1 mRNA expression was analyzed in primary human foreskin fibroblasts (HFFs) and macrophage-derived THP-1 cells infected with laboratory or clinical HCMV strains and subjected to reverse transcription-quantitative PCR (RT-qPCR) analysis at day 1 and 2 post-infection (dpi). This evidence concerns the gene SAMHD1 and infection.