EYA4 and hearing loss disorder: Also replicated in our analysis (notably, at genome-wide significance in the UK Biobank) were two SNPs previously reported at a suggestive significance level, in or near genes that cause Mendelian forms of hearing loss: rs9493627, a missense SNP in EYA4[4] (p = 7.7x10-10); rs2877561, a synonymous variant in ILDR1[4] (p = 1.1x10-8).