Head and neck squamous cell carcinoma, esophageal squamous cell carcinoma, breast cancer, and non-small cell lung carcinoma show an increased expression of TNFAIP8 mRNA (Patel et al., 1997; Dong et al., 2010; Hadisaputri et al., 2012). Here, TNFAIP8 is linked to head and neck squamous cell carcinoma.