Wang et al., (2014) and Weiwei et al., (2014) found a significant association of MTHFR-C677T transition and folate intake with risk of breast cancer, and they reported a significant interaction between folate intake and MTHFR-C677T transition (Wang et al., 2014; Weiwei et al., 2014). Here, MTHFR is linked to breast carcinoma.