So far, two types of AIH have been established: type 1 (AIH-1) is characterized by the presence of antinuclear antibodies (ANA) and anti-smooth muscle antibodies (anti-SMA) and type 2 (AIH-2) is defined by the positivity for anti-liver kidney microsomal type 1 antibodies (anti-LKM-1) or presence of anti-liver cytosol type 1 antibody (anti-LC-1) (Liberal et al., 2013). Here, SMN1 is linked to autoimmune hepatitis.