However, YTHDF2 expression was lower in head and neck squamous cell carcinoma, KICH (kidney chromophobe), KIRC (kidney renal clear cell carcinoma), kidney renal papillary cell carcinoma, and LIHC (liver hepatocellular carcinoma) tissues than in adjacent normal tissues. The gene discussed is YTHDF2; the disease is head and neck squamous cell carcinoma.