APOBEC3B and cancer: Although several APOBEC3s have been implicated in cancer mutagenesis including APOBEC3A (A3A) and APOBEC3H (A3H) (Chan et al., 2015; Nik-Zainal et al., 2014; Starrett et al., 2016; Taylor et al., 2013), a particularly strong case can be made for APOBEC3B (A3B).