In order to explore the effect of TRPV2 in cell morphology, we expressed TRPV2-GFP in different non-neuronal cell lines like ChoKI (Chinese hamster ovary), HaCaT (keratinocyte cell line), HEK (kidney cell line) and SaOS (primary osteosarcoma). This evidence concerns the gene TRPV2 and osteosarcoma.