PRMT5 and colon adenocarcinoma: Interestingly, we also observed that the expression level of YBX1 (x-axis) and PRMT5 (y-axis) were significantly positively correlated in COAD patients, suggesting that this YBX1-PRMT5 correlation could serve as the basis for future patient stratification and identification of patients who are likely to benefit from inhibition of YBX1-PRMT5 cooperativity.