A representative list of these genes is summarized in the heatmap shown in Fig. 2A. Among the up-regulated genes observed in lymphomas from Lck-Dlx5;Lck-MyrAkt2 mice, Notch, Myc, and Ccnd1 were previously reported to be upregulated in lymphomas from Lck-Dlx5 mice, and Myc was previously shown to be upregulated in Lck-MyrAkt2 mice22. This evidence concerns the gene CCND1 and lymphoma.