To help elucidate the mechanism underlying lymphomagenesis in Lck-Dlx5;Lck-MyrAkt2 mice, RNA-seq analysis was performed on T cell lymphoma cells from three Lck-Dlx5;Lck-MyrAkt2 mice (DP240, DP242, DP352) and thymic T cells from three wild-type (WT) mice. The gene discussed is DLX5; the disease is T-cell non-Hodgkin lymphoma.