FMR1 and Zika virus infectious disease: Soto-Acosta and colleagues hypothesized that because FMRP is a known repressor of cellular mRNA translation, that translation of ZIKV is inhibited by FMRP early after infection thus reducing ZIKV infection, but as infection progresses, sfRNA antagonizes FMRP function leading to increased expression of FMRP target genes.