SLC22A17 and hemochromatosis type 1: Interestingly, urinary tract infection decreases Fe accumulation in the distal nephron of hemochromatosis mouse models (Houamel et al., 2016) along with decreased SLC22A17 expression (Betten et al., 2018), supporting a role for SLC22A17 in mediating Fe uptake in the distal nephron.