CD4 and Huntington disease: To further characterize the memory CD4+ Treg circulating compartment, mTreg Th-like subsets were determined in PBMC from HD and HCPS gating in CD25+CD127low/−CD45RA−CCR4+ follow by determination of Th1-like Treg (CXCR3+CCR6−), Th2-like Treg (CXCR3−CCR6−), and Th17-like Treg (CXCR3−CCR6+) (Figure 2A).